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Third-party-funded project

Title:
The role of stress- and mitogen induced signaling pathway in the regulation of keratinocyte proliferation and differentation

Project management at the University of Würzburg:

Participating scientists:

Abstract:
The misfunction of proliferation- and differentiation processes in keratinocytes plays a critical role in the pathogenesis of several skin diseases. The intracellular signaling pathways that control the balance between proliferation and differentation of skin cells are not well defined. In the project we will functionally characterise such signaling pathways with a strong focus on MAP kinase cascades. The project will be perfomed in collaboration with Dr. Matthias Goebeler from the Dermatology Department, University of Würzburg. The collaborative study is supposed to form a bridge between basic research and the clinic.

Key words:
    Skin differentiation
    MAP kinases
    keratinocytes

Projekt period: from 07.2001 to 06.2003

Funding institution:
DFG ,Granting date: 18.07.2001

Publications: