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Third-party-funded project

Title:
Modification of the immunogenic potential of insulin producing beta cells of the endocrine pancreas by genetic engineering

Project management at the University of Würzburg:

• PD Dr. med. J. Seufert ,Tel: 0931/201-70170,Fax: 0931-201-70680,Mail: j.seufert@mail.uni.wuerzburg.de

Participating scientists:

• Dipl. Biol. M. Lazariotou

Abstract:
In this research project strategies for suppression of the immunogenicity of transplanted pancreatic islets will be developed.

Key words:
    endocrine pancreas
    immunogenicity

Projekt period: from 08.2000 to 08.2003

Funding institution:
Bund ( IZKF Würzburg ) ,Granting date: 10.08.2000

Publications:

• Seufert J et al.. (2001). Suppression of the immunogenic potential of pancreatic beta-cells by genetic reduction of autoantigenic glutamic acid decarboxylase (GAD) expression. In Exp.Clin.Endocrinol.Diabetes 110 (Suppl. 1):42 . (conference publication)