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Third-party-funded project

Title:
The role of the nuclear hormone receptor PPARgamma during pathogenesis of esophagitis-metaplasia-dysplasia-carcinoma sequence of Barrett?s carcinoma.

Project management at the University of Würzburg:

• Dr. med. O. Al-Taie ,Tel: 0931/201-70850,Fax: 0931-201-70090,Mail: al-taie_o@klinik.uni-wuerzburg.de

Participating scientists:

• PD Dr. med. J. Seufert
• Prof. Dr. med. M. Scheurlen

Abstract:
In this research project the role of PPARgamma for the regulation of cell proliferation and differentiation during development of Barrett?s carcinoma is analyzed.

Key words:
    PPARgamma
    Barrett?s carcinoma

Projekt period: from 01.2001 to 01.2003

Funding institution:
Sonstige öffentliche Mittel ( Universitätsbund Würzburg (Aktenzeichen 02-49) ) ,Granting date: 01.01.2001

Publications:

• Al-Taie O et al.. (2002). Expression und funktionelle Charakterisierung von PPARg im humanen Barrett-Ösophagus und Barrettkarzinom. Z .Gastroenterol. 8:640, (scientific article)
• Al-Taie O et al.. (2002). Expression and Functional Characterization of PPARg in Human Barrett's Epithelium and Barrett's Adenocarcinoma Cells. In Proceedings of the Digestive Disease Week (DDW): A-458 . (conference publication)