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Research focus:  

Klinik und Poliklinik für Hals-, Nasen- u. Ohrenkranke
Josef-Schneider-Str. 11, 97080 Würzburg
Mail: marianne.schmidt@mail.uni-wuerzburg.de
Url: http://www.hno.uni-wuerzburg.de

Scientific members:

   Scientific assistants:

Research foci (and basic equipment-based research projects):
Using northern hybridizations we analyzed the expression of bmp-2 (bone morphogenetic protein-2) in fibroblasts and keratinocytes cultivated of cholesteatomas and external ear canal skin (EACS).

Results:
Fibroblasts cultivated of cholesteatomas express bmp-2 while EACS fibroblasts do not. bmp-2 expression can be stimulated in EACS fibroblasts by cultivation with extracts made of cholesteatoma debris. Keratinocytes of both cholesteatoma and EACS express bmp-2 konstitutively.