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Third-party-funded project

Molecular genetic of sporadic motoneuron diseases

Project management at the University of Würzburg:

Participating scientists:

Candidate genes which contribute to the pathogenesis of sporadic motoneuron disease are so far ill defined. During the course of this project, a series of candidate genes were identified, and in particular the role of CNTF and LIF gene mutations characterised with respect to their function in sporadic motoneuron disease. This was achieved by cross-breeding various mouse models and investigation of cooperative effects between various gene products in maintenance of motoneurons.

Key words:
    Amyotrophic lateral sclerosis
    Motoneuron diseases

Projekt period: from 01.1995 to 12.2001

Funding institution:
DFG ( To 61/8-3 und 61/8-4 ) ,Granting date: 07.07.1997
Landeshaushalt Wissenschaftsministerium

Preceding project:
DFG To 61/8-1


Institute for Clinical Neurobiology