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Third-party-funded project

Title:
Molecular genetics of infertility

Project management at the University of Würzburg:

• Prof. Dr. med. Michael Sendtner ,Tel: 201-49767,Fax: 201-49788,Mail: sendtner@mail.uni-wuerzburg.de

Participating scientists:

• Dr. med. Ralf Giess

Abstract:
Inactivation of the gene for LIF leads to infertility in female mice. We have investigated the genotype of infertile patients, and found that mutations in the LIF gene are significantly more frequent in these patients in comparison to controls.

Key words:
    Infertility
    Genetics
    Transgenic mice

Projekt period: from 01.1998 to 12.2001

Funding institution:
DFG ( To 61/8-3 und 61/8-4 ) ,Granting date: 07.07.1997
Landeshaushalt Wissenschaftsministerium

Publications:

• Giess et al.. (1999). Leukemia inhibitory factor gene mutations in infertile women. Mol. Human Reproduction 5, (scientific article)

Links:
Institute for Clinical Neurobiology