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Third-party-funded project

Role of neurotrophic factors in retinal degeneration

Project management at the University of Würzburg:

Neurotrophic factors also support survival of photoreceptors in the developing and postnatal retina. We have developed recombinant adenovirus for transfer of CNTF and BDNF, and found that transfer of the CNTF gene prevents degeneration of photoreceptors in the RDS mouse model for retinis pigmentosa.

Key words:
    Cell death
    Retinal degeneration
    Gene therapy

Projekt period: from 01.1998 to 12.1999

Funding institution:
DFG ( To 61/8-3 und 61/8-4 ) ,Granting date: 07.07.1997
Landeshaushalt Wissenschaftsministerium

Preceding project:
DFG To 61/8-1


Institute for Clinical Neurobiology