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Third-party-funded project

Title:
Developmental requirement for gp130 signalling in neuronal survival and astrocyte differentiation

Project management at the University of Würzburg:

Participating scientists:

Abstract:
Members of the CNTF-family do not only support survival of neurons, but also differentiation of glial cells. We could show, that mice in which the gp130 receptor component is inactivated do not only exhibit reduced survival of sensory and motoneurons during development, but also specific defects in differentiation of astrocytes.

Key words:
    Stem cells
    Differentiation
    Apoptosis

Projekt period: from 01.1998 to 12.1999

Funding institution:
Sonstige öffentliche Mittel ( Human Frontiers of Science HFSPO ) ,Granting date: 19.09.1997

Publications:

Links:
Institute for Clinical Neurobiology