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Third-party-funded project

Pathogenesis of radiation induced lung fibrosis: Interaction of different cell populations with respect to pro-fibrotic cytokines in a coculture model.

Project management at the University of Würzburg:

Participating scientists:

Purpose of the project is the analysis of basic interaction between pulmonal fibroblasts, macrophages and epithelial cells in pathogenesis of radiation induced lung fibrosis in a coculture model. We focus on fibroblasts with their ability to produce profibrotic cytokines and to perform an autoactivation. The role of antagonists of profibrotic cytokines will be determined.

Key words:
    radiation fibrosis
    TGF beta

Projekt period: from 11.2001 to 11.2003

Funding institution:
Sonstige Stiftung ( Deutsche Krebshilfe ) ,Granting date: 05.07.2001