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Third-party-funded project

Title:
Anti-TGF beta gene therapy for prevention of radiation induced lung fibrosis

Project management at the University of Würzburg:

Participating scientists:

Abstract:
The profibrotic cytokine TGF beta has been assigned a central role in pathogenesis of radiation induced lung fobrosis. The project has been designed to determine the possibility to avoid radiation induced lung fibrosis folowing partial lung irradiation in an in vivo model by antagonizing TGF beta by means of adenoviral gene transfer.

Key words:
    Adenoviral gene transfer
    radiation fibrosis
    radiation fibrosis

Projekt period: from 01.2003 to 01.2005

Funding institution:
DFG ( DFG ) ,Granting date: 05.08.2002