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Third-party-funded project

Diagnostics of endothelial dysfunction

Project management at the University of Würzburg:

Participating scientists:

Aim of this project is the development of novel biochemical markers and functional paramaters for the human vascular endothelium. In particular, the analysis of VASP (vasodialtor-stimulated phosphoprotein) phosphorylation as indicator of the functional integrity of the endothelium is investigated. Three main question are addressed :
? The analysis of VASP phosphorylation as marker for endothelial functions in various animal model.
? The analysis of P-VASP as marker of endothelial functions in human vessel wall samples
? Developmemt of a P-VASP assay suitable for whole blood

This project is a collaboration with vasopharm Biotech GmbH (Wuerzburg)

Key words:
    NO-cGMP Signalling
    Endothelial Dysfunction

Projekt period: from 12.2001 to 09.2002

Funding institution:
Wirtschaftsunternehmen ( Vasopharm Biotech ) ,Granting date: 19.12.2001


Vasopharm Biotech