Institut für Klin.Biochemie und Pathobiochemie
Josef-Schneider-Str. 2, 97080 Würzburg
Research foci (and basic equipment-based research projects):
A central goal of the institute is to elucidate the physiological, pathophysiological and diagnostic role and potential of inter- and intracellular signal transduction pathways which regulate cardiovascular cells, i.e. cardiac myocytes, vascular smooth muscle cells, endothelial cells, platelets, and inflammatory cells. Biochemical and pathobiochemical elucidation of these pathways is the main focus of the department of clinical biochemistry and may contribute to a better understanding of pathogenesis and useful therapeutic interventions of major cardiovascular diseases, i.e. hypertension, arteriosclerosis, coronary heart disease, heart failure and thrombotic/bleeding disorders. More recently, the role of established and novel genetically determined risk factors for cardiovascular diseases became the focus of the C3-professorship ?Clinical Molecular Biology?. Another area of research, primarily within the department of clinical chemistry (laboratory medicine) addresses the diagnostic and and genetic analysis of inherited and acquired thrombophilic and hemophilic diseases. The research of the institute is supported to a large extent by project-oriented extramural grants. 1999 - July/2002, 70 original articles and 14 peer-evaluated reviews were published in international journals by members of our institute. In addition, members and students of the institute completed 2 Habilitationen and 13 dissertations. The research of the institute also contributed to the successful establishment of vasopharm BIOTECH GmbH in Wuerzburg.
See publication list (Ergebnisse deutsch) and the reports of the individual projects.
Rudolf-Virchow Zentrum Würzburg
Interdisziplinäres Zentrum für Klinische Forschung
Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg