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Third-party-funded project

Title:
Dynamics of the threedimensional folding and 3D-structure of tRNA

Project management at the University of Würzburg:

• Professor Dr. Hans J. Gross

Participating scientists:

• Dr. Victor Serebrov
• Dr. Konstantin Vassilenko

Abstract:
Stability and dynamics of 2D- and 3D-structures of tRNAs was determined by fluorescence titration, circular dichroism and thermal conformation transitions and correlated with biological properties.

Key words:
    tRNA tertiary structure
    tRNA

Projekt period: from 09.1997 to 09.2002

Funding institution:
VW-Stiftung ,Granting date: 11.07.1996

Publications:

• V. Serebrov, R.J. Clarke, H.J. Gross & L. Kisselev:. (2001). Mg2+-induced tRNA Folding. (monograph)
• V. Serebrov, K. Vassilenko, N. Kholod, H.J. Gross & L. Kisselev:. (1998). Mg2+ binding and structural stability of mature and in vitro synthesized unmodified Escherichia colitRNA(Phe). (monograph)