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Third-party-funded project

Title:
Nociceptive properties of somatic and visceral afferents under normal and pathological conditions in different species.

Project management at the University of Würzburg:

Participating scientists:

Abstract:
The aim of this project was to compare neurophysiological and neurohistological studies in vivo and in vitro currently performed by scientists of the SFB 353 in Würzburg and Erlangen and in the laboratory of Profs. Kumazawa and Mizumura, dealing with the peripheral mechanisms of nociception. The project included electrophysiological studies with inflammatory mediators and other algogenic substances involved in signal transduction as well as light and electron microscopic immunohistochemical examinations of the neuropeptide content of nociceptors in different tissues of varying species.

Key words:
    Nociceptor
    Signal transduction
    Neuropeptides
    Substance P
    Calcitonin gene-related peptide
    Inflammatory mediators
    Knee joint
    Testis
    Spermatic nerve
    Dorsal root ganglia
    Electrophysiology
    Immuncytochemistry
    Retrograde tracing

Projekt period: from 06.1994 to 06.1996

Funding institution:
DFG

Publications: