Novel approaches to combat multidrug resistance (MDR) in pathogenic yeast
Project management at the University of Würzburg:
Identification and characterization of regulatory networks in Candida albicans which affect expression of multiple drug resistance proteins.
multiple drug resistance
from 12.2001 to 11.2004
EU ( FP5 ) ,Granting date: 09.11.2001
- Wirsching S, Michel S, Kohler G, Morschhäuser J..
(2000). Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor. J. Bacteriol., (scientific article)
- Morschhäuser J..
(2002). The genetic basis of fluconazole resistance development in Candida albicans. Biochim. Biophys. Acta, (scientific article)