Direct Genotoxicity of the Carcinogenic Bacterium Helicobacter Pylori
Project management at the University of Würzburg:
Epidemiology shows a connection between infections of the stomach with Helicobacter Pylori and the incidence of stomach carcinomas. However, the mechanisms of carcinogenesis are not understood. We intend to characterize the observed in vitro genotoxity of the bacterium. Particular attention will be devoted to known Helicobacter-pathogenicity-factors and geographical HP-strain-differences.
Projekt period: from 07.2002 to 06.2004