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Third-party-funded project

Influence of size of different ceramic and titanium particles in particle disease - a macrophages culture study

Project management at the University of Würzburg:

Participating scientists:

In this project the influence of particle size of different particle materials in a macrophage modell (differentiated THP-1 cells) is analysed. Particularly, Al2O3 particles result in a reduced sekretion of the osteoresorptive cytokine TNF alpha, compared to metal particles. Due to the known low level of waer debris resulting from ceramic implants, these materials can be recommended for endoprothetic procedures.

Key words:
    particle disease
    macrophage cell culture

Projekt period: from 01.1999 to 01.2003