C 3-Professur für Humangenetik (Weber)
Am Hubland, 97074 Würzburg
Research foci (and basic equipment-based research projects):
The hereditary macular dystrophies are a heterogenous group of disorders characterized by loss of central vision secondary to cone as well as cone/rod photoreceptor degeneration. In most cases the molecular basis of the degenerative changes in the macula is unknown. The isolation and characterization of genes involved in the pathogeneses of the various macular dystrophies such as Best disease, Stargardt disease, X-linked juvenile retinoschisis or Sorsby fundus dystrophy, may provide new insights into the mechanisms of disease and thus may help to expand our knowledge of retinal function and dysfunction. Consequently, this may lead to novel approaches for the prevention and treatment of the macular dystrophies.