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Third-party-funded project

Title:
Parapneumonic empyema and complicated parapneumonic effusions in children and adolescents under 18 years of age in Germany

Project management at the University of Würzburg:

Participating scientists:

Abstract:
An increase in the incidence of paediatric parapneumonic effusions and empyema (PPE/PE) has been observed worldwide. So far there is a lack of data from PPE/PE in children and adolescents under 18 years in Germany after introduction of the general pneumococcal vaccination program in 2006. The objective of this prospective surveillance-study is to determine causes, therapeutical management and incidence in children with PPE/PE in Germany, using the ?German Surveillance Unit for Rare Diseases in Childhood? (ESPED). Children <18 years of age with a diagnosis of pneumonia accompanied by pleural effusion persisting for at least 8 days or necessitating pleural drainage were included. For the first time, it is therefor possible to collect population based data about pathogen distribution, course and management of PPE/PE in children and adolescents below 18 years of age in Germany.

Key words:
    pleural empyema
    pleural effusion
    pneumonia
    pneumococci

Projekt period: from 10.2010 to 09.2018

Funding institution:
Wirtschaftsunternehmen ( Pfizer Pharma GmbH Berlin, Deutschland )