Research focus: |
Lehrstuhl für Haut- und Geschlechtskrankheiten
Josef-Schneider-Str.2, 97080 Würzburg Mail: gillitzer_r@haut.uni-wuerzbrurg.de Url: |
Scientific members:
Outside lecturer:
Scientific assistants:
Other participating persons and organisations:
Research foci (and basic equipment-based research projects):
1) Mechanism of wound healing
2) Pathogenesis of Psoriasis
3) Role of chemokines in inflammatory reactions of the skin
Results:
Literature:
KLEINE-LOWINSKI K, GILLITZER R, KÜHNE-HEID R, RÖSL F: Monocyte-chemoattractant proetin-1 (MCP-1) gene expression in cervical intraepithelial neoplasias and cervical carcinoma. Int J Cancer 82(1):6, 1999
R. GILLITZER equal first author
GOEBELER M, KILIAN K, GILLITZER R, KUNZ M, YOSHIMURA T, BRÖCKER EB, RAPPUR, LUDWIG S: The MKK6/p38 stress kinase cascade is involved in TNF-induced activation of endothelial cells. Blood 93:857-865, 1999
YOSHIMURA T, TAKEYA M, OGATA H, YAMASHIRO S, MODI WS, GILLITZER R. . Molecular cloning of the guinea pig GRO and its rapid expression in the tissues of lipopolysaccharide-injected guinea pig. Int. Arch. Allergy Immunol. 119:101, 1999
HARTMANN A, KUNZ M, KÖSTLIN S, GILLITZER R, TOKSOY A, BRÖCKER EB, KLEIN CE: Hypoxia-induced up-regulation of Angiogenin in human malignant melanoma. Cancer Research 59:1578-1583, 1999
KUNZ M, TOKSOY A; GOEBELER M, ENGELHARDT E, BRÖCKER EB, GILLITZER R. High expression of the lymphoattractant CXC chemokine Mig is associated with strong infiltration of T cells in human malignant melanoma. J Path 189:552-558, 1999
KUNZ M, HARTMANN A, FLORY E, TOKSOY A, KOCZAN D, THIESEN HJ, RAPP UR, BRÖCKER EB, GILLITZER R. Hypoxia-induced upregulation of interleukin-8 in human malignant melanoma: A potential mechanism for high tumor aggressiveness. Am J Path 155:753-763, 1999
TRAUTMANN A, TOKSOY A, ENGELHARDT E, BRÖCKER EB, GILLITZER R: Mast cell involvement in normal human skin wound healing: expression of monocyte chemoattractant protein-1 is correlated with recruitment of mast cells which synthesize interleukin-4 in vivo. J Path 190:100-106, 2000
SALAIZO-SUAZO N, VOLKOW P, PEREZ-TAMAYO R, MOLL H, GILLITZER R, PEREZ-TORRES A, PEREZ-MONTFORT R, DELGADO DOMINGUEZ J, VELASCO_CASTREJON O, CRIPPA M, BECKER I. Treatment of two patients with diffuse cutaneus Leishmaniasis caused by Leishmania mexicana modified the immunohistological profile but not the disease outcome. Trop Med Inter Health 4:801-811, 2000
KÖNIG A, KRENN V. TOKSOY A, GERHARD N, GILLITZER R. Mig, GROalpha and RANTES messenger RNA expression in lining layer, infiltrates and different leukocyte populations of synovial tissue from patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis. Virchows Archiv 436:449-458, 2000
ECK M, SCHMAUSSER B, TOKSOY A, SCHELLER K, KRAUS M, MENZEL T, MÜLLER-HERMELINK HK, GILLITZER R. C-X-C chemokines Groa/Il-8 and IP-10/Mig in Helicobacter pylori gastritis. Clin Exp Immunol 122:192-199, 2000
GOEBELER M, GILLITZER R, KILIAN K, UTZEL K, BRÖCKER EB, RAPP UR, LUDWIG S. Multiple signaling pathways regulate NF-kB-dependant transcription of the monocyte chemoattractant proetin-1 gene in primary endothelial cells. Blood 97:46-55, 2001
GOEBELER M, TRAUTMANN A, TOKSOY A, BRÖCKER E-B, VOSS A, GILLITZER R. Differential and sequential expression of multiple chemokines regulates effector cell recruitment during elicitation of allergic contact dermatitis. Am J Pathol 158:431-440, 2001
SPANDAU U, BRÖCKER EB, KÄMPGEN E, GILLITZER R. CC and CXC chemokines are differentially expressed in Erythema multiforme. Arch Dermatol 138:1027-1033, 2002
PASPARAKIS M, COURTOIS G, HAFNER M, SCHMIDT-SUPPRIAN M, NENCI A, TOKSOY A, KRAMPERT M, GOEBELER M, GILLITZER R, ISRAEL A, KRIEG T, RAJEWSKY K, HAASE I. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417:861-866, 2002
Übersichtsartikel
GILLITZER R. TOKSOY A, VOSS A. The role of chemokines during human wound healing. Zentralblatt für Chirurugie S1,56-60, 2000
GILLITZER R. Inflammation in human skin: a model to study chemokine-mediated leukocyte migration in vivo. J Path 194:393-394, 2001
GILLITZER R, GOEBELER M. Chemokines in cutaneous wound healing. J Leuc Biol
69:513-521, 2001
GILLITZER R. Modern Wound management. Hautarzt 53:130-145, 2002-11-24