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Third-party-funded project

Title:
Rational drug design against malaria

Project management at the University of Würzburg:

Participating scientists:

Abstract:
Cellular redox metabolism is involved in regulation of cell proliferation and differentiation as well as in the control of various metabolic pathways; furthermore, the malarial parasite Plasmodium falciparum is very susceptible to oxidative challenge.Therefore, we are interested in studying the redox metbolism of parasitized cells: as a contribution to cell biology and the development of new chwmotherapeutic approaches.

Key words:
    malaria
    Plasmodium falciparum
    oxidative stress
    glutathione reductase
    thioredoxin reductase

Projekt period: from 01.0000 to 10.0001

Funding institution:
DFG ,Granting date: 01.01.2000

Publications: