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Third-party-funded project

Investigations on the Biosynthesis of Naturally Occurring Diazepam-Like 1,4-Benzodiazepines

Project management at the University of Würzburg:

Participating scientists:

Completey unexpectedly, Valium-type benzodiazepines, which are widely used as synthetic anxiolytics, have recently been found to be natural products. Our project aimed at the exploration of their biosynthetic origin by chemo-enzymatic studies in mould strains and plant cell cultures to identify presumable intermediates of naturally formed benzodiazepines.

Key words:
    Biogenesis in Plants and Mould Strains
    Diazepam-Like Benzodiazepines

Projekt period: from 08.1998 to 05.2001

Funding institution:
DFG ( Normalverfahren, Förderkennzeichen: BR 699/6-1 ) ,Granting date: 24.06.1998