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Third-party-funded project

Title:
"New Agents from Tropical Plants and Soil Organisms: Isolation, Structure Elucidation, and Chemical Modification" within the Collaborative Research Project entitled "Molecular Interaction between Targets and Natural Products as a Tool for the Identification of New Agents and Agent Models for Agrochemical and Pharmaceutical Research" (managed by the BASF AG)

Project management at the University of Würzburg:

Participating scientists:

Abstract:
Tropical medicinal plants produce a variety of biologically active secondary metabolites, a rich, but still largely untapped source of novel leads for the development of new agrochemicals and pharmaceutics. After selection of plants by ethnobotanical criteria, biological activities of plant extracts and isolated compounds were investigated by special molecular test systems (established by the BASF AG). Selected fields of indication are herbicidal, fungicidal, anti-tumor, CNS, and anti-hypertensive activities. According to these criteria, crude plant extracts of different polarity will be tested to identify the active principle.

Key words:
    Ancistrocladaceae and Dioncophyllaceae
    Pharmaceuticals
    Agrochemicals
    Novel Leads
    Bioassay-guided Search for New Agents
    Tropical Medicinal Plants
    Dioncophylline

Projekt period: from 11.1997 to 10.2000

Funding institution:
Bund ( Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie , BMBF ) ,Granting date: 28.11.1997
Wirtschaftsunternehmen ( BASF AG )

Preceding project:
BASF/BMBF-Verbundprojekt (1994 -1997), Förderkennzeichen: 0310722

Publications:

Links:
Research Group Prof. Bringmann - Homepage