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Third-party-funded project

Title:
Anti-nociceptive mechanisms in the inflamed knee joint of the rat

Project management at the University of Würzburg:

Participating scientists:

Abstract:
Recent studies showed that opioids not only act on the central nervous
system, but moreover they exert peripheral analgetic effects. Using an
arthritis model of the rat knee joint we examined the mechanisms of their
analgesic action, especially which mediators are able stimulate the release
of opioids and in which way they interact.

Key words:
    Pain
    Neuropeptides
    Opioids
    Opioid receptors
    Mechanoreceptors
    Articular afferents
    Inflammation
    Electrophysiology

Projekt period: from 01.98 to 12.2000

Funding institution:
DFG ( SFB )

Preceding project:
Neuropeptidrezeptoren, SFB353/B10

Publications: