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Third-party-funded project

Title:
Development of cell culture models for analysis of toxopasma gondii infection in the nervous system

Project management at the University of Würzburg:

• Prof. Dr. med. Michael Sendtner Sendtner ,Tel: 201-49767,Fax: 201-49788,Mail: sendtner@mail.uni-wuerzburg.de

Participating scientists:

• Prof. Dr. rer. nat. U. Gross
• Dr. Mario Giraldo-Velasquez
• Dr. C. G. Luder

Abstract:
We have established a cell culture model for infection of Toxoplasma Gondii. This model appears useful for analysis of interaction between the cellular parasite and the host cell.

Key words:
    Toxoplasma gondii
    Cell culture
    Neuronal cells
    Infection

Projekt period: from 01.1997 to 12.2001

Funding institution:
Landeshaushalt Wissenschaftsministerium ,Granting date: 07.07.1997
DFG ( To 61/8-3 und 61/8-4 )

Publications:

• Luder C.G.. (1999). Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes, and microglial cells for the intracerebral development and stage differentiation. Exp. Parasitol. Vol. 93 (1), 23-32, (scientific article)

Links:
Institute for Clinical Neurobiology