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Third-party-funded project

Title:
The role of the neuronal apoptosis inhibitory protein during natural cell death and neurodegenerative processes

Project management at the University of Würzburg:

Participating scientists:

Abstract:
The function of the NAIP protein, a member of the gene family of BIR-domain inhibitors of caspases was investigated in PC12 cells. We found that this protein prevents cell death but also inhibits axon growth, by this means prohibiting therapeutic strategies for gene transfer of NAIP in neurodegenarative disorders.

Key words:
    Amyotrophic lateral sclerosis
    Motoneuron disease
    Axon growth

Projekt period: since 01.1997

Funding institution:
Landeshaushalt Wissenschaftsministerium ,Granting date: 07.07.1997
DFG ( To 61/8-3 und 61/8-4 )

Preceding project:
DFG To 61/8-1

Publications:

Links:
Institute for Clinical Neurobiology