Analysis of neuromuscular insufficency in rotator cuff disease
Project management at the University of Würzburg:
Molecular genetic markers of denervation (expression of fetal Acetylcholine receptor) and immunhistochemical findings are evaluated in biopsies of human rotator cuff and deltoid muscles of patients suffering from subacromial pain. These parameters are correlated to clinical and neurophysiological findings.
In biopsies (supraspinatus and deltoid muscle) of 265 patients suffering from rotator cuff disease in a surprising high percentage (63.7%) markers of chronic denervation were found. The deltoid muscle was involved especially in massive tears.
Projekt period: from 07.2000 to 06.2003