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Research focus:  

Klinische Forschergruppe Stammzell-Differenzierung
Brettreichstrasse 11, D-97074 Würzburg
Mail: f-jakob.klh@mail.uni-wuerzburg.de
Url: http://www.uni-wuerzburg.de/orthopaedie

Scientific members:

   Professors:

   Outside lecturer:

   Scientific assistants:

   Other participating persons and organisations:

Research foci (and basic equipment-based research projects):
- Osteogenic Stem Cell Differentiation and Therapy of Bone Loss
- Recombinant Proteins (PD Dr. N. Schütze)
- Genomics and Proteomics of stem cells (Dr. R. Ebert, Dr. K. Paunescu)
- Tissue Engineering and Mesenchymal Stem Cells (Dr. U. Nöth)
-

Results:
Results are shown in single project reports (KFG projects, link Experimental and Clinical Osteology.

Rewards and prizes:
- Lechner A., Schütze N., Siggelkow H., Seufert J., Jakob F. (2000) "The immediate early gene product hCYR61 localises to the
secretory pathway in human osteoblasts". Bone 27:53-60 Nomination for the "Best Paper Award" 2000 in "Bone" by the International
Society for Bone and Mineral Research.
- Rader C., Baumann B., Schütze N., Jakob F., Eulert J. (2001) "Regulation of Gene products in a human Particle-Disease-Model" 1. Poster Award of the Association of Orthopedic Surgeons
in North Germany e.V.
- Schütze N., Lechner A., Müller J., Eulert J., Jakob F. Expression and regulation of the immediate early gene
product hCYR61 in human osteoblasts. "Mario Boni Award" 2000 of the European Orthopedic Research Society
- Schütze N., Reichel S., Barthelmes U., Rücker N., Pfeufer J., Lechner A., Jakob F. (2001) "The human Protein A kinase adaptor protein 2 is a TNF?
regulated gene in human osteoblasts and localizes to the actin cytoskeleton". Plenary Poster bei der Jahrestagung der American
Society for Bone and Mineral Research, Phoenix, USA
- Schütze N: Travel Award Annual Meeting of osteologic Societies "Osteologie
2002", Graz, Austria

Equipment:
Laboratories comprising tools for basic science research under conditions of S1, partly allowance for radioactivity. Apparitve
Laboratory equipment: Light-Cycler, Phosphor-Imager, FPLC-Equipment, Automatic Sequencer, Fluorescence Microscopy

Links:
Experimental and Clinical Osteology